qpatch assay software v5.0 Search Results


qpatch assay software v5.0  (Sophion Bioscience)
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Sophion Bioscience qpatch assay software v5.0
Qpatch Assay Software V5.0, supplied by Sophion Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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qpatch assay software v5.0 - by Bioz Stars, 2026-03
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qpatch assay software v5.0  (Biolin Scientific)
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Biolin Scientific qpatch assay software v5.0
Inhibition of hNa V 1.1 –hNa V 1.7 heterologously expressed in HEK293 cells (for hNa V 1.1 –hNa V 1.4) or CHO cells (for hNa V 1.6 -hNa V 1.8). Data points are mean ± SEM of three independent cells ( n = 3) for hNa V 1.3, four independent cells ( n = 4) for hNa V 1.1, hNa V 1.4 and hNa V 1.7, six independent cells ( n = 6) for hNa V 1.2 and of seven independent cells ( n = 7) for hNa V 1.6. Currents were recorded using automated patch-clamp electrophysiology <t>(QPatch</t> 16X). Fitting of the Hill equation to the data yielded IC 50 values of (in nM) 3.3 ± 1.1, 6.8 ± 1.5, 7.2 ± 1.6, 8.4 ± 1.8, 11.9 ± 2.2 and 369 ± 196 for hNa V 1.7, hNa V 1.6 and hNa V 1.3, hNa V 1.1, hNa V 1.2 and hNa V 1.4, respectively. hNa V 1.5 and hNa V 1.8 were insensitive to the toxins up to 1 μM.
Qpatch Assay Software V5.0, supplied by Biolin Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/qpatch assay software v5.0/product/Biolin Scientific
Average 90 stars, based on 1 article reviews
qpatch assay software v5.0 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

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Inhibition of hNa V 1.1 –hNa V 1.7 heterologously expressed in HEK293 cells (for hNa V 1.1 –hNa V 1.4) or CHO cells (for hNa V 1.6 -hNa V 1.8). Data points are mean ± SEM of three independent cells ( n = 3) for hNa V 1.3, four independent cells ( n = 4) for hNa V 1.1, hNa V 1.4 and hNa V 1.7, six independent cells ( n = 6) for hNa V 1.2 and of seven independent cells ( n = 7) for hNa V 1.6. Currents were recorded using automated patch-clamp electrophysiology (QPatch 16X). Fitting of the Hill equation to the data yielded IC 50 values of (in nM) 3.3 ± 1.1, 6.8 ± 1.5, 7.2 ± 1.6, 8.4 ± 1.8, 11.9 ± 2.2 and 369 ± 196 for hNa V 1.7, hNa V 1.6 and hNa V 1.3, hNa V 1.1, hNa V 1.2 and hNa V 1.4, respectively. hNa V 1.5 and hNa V 1.8 were insensitive to the toxins up to 1 μM.

Journal: PLoS ONE

Article Title: The structure, dynamics and selectivity profile of a Na V 1.7 potency-optimised huwentoxin-IV variant

doi: 10.1371/journal.pone.0173551

Figure Lengend Snippet: Inhibition of hNa V 1.1 –hNa V 1.7 heterologously expressed in HEK293 cells (for hNa V 1.1 –hNa V 1.4) or CHO cells (for hNa V 1.6 -hNa V 1.8). Data points are mean ± SEM of three independent cells ( n = 3) for hNa V 1.3, four independent cells ( n = 4) for hNa V 1.1, hNa V 1.4 and hNa V 1.7, six independent cells ( n = 6) for hNa V 1.2 and of seven independent cells ( n = 7) for hNa V 1.6. Currents were recorded using automated patch-clamp electrophysiology (QPatch 16X). Fitting of the Hill equation to the data yielded IC 50 values of (in nM) 3.3 ± 1.1, 6.8 ± 1.5, 7.2 ± 1.6, 8.4 ± 1.8, 11.9 ± 2.2 and 369 ± 196 for hNa V 1.7, hNa V 1.6 and hNa V 1.3, hNa V 1.1, hNa V 1.2 and hNa V 1.4, respectively. hNa V 1.5 and hNa V 1.8 were insensitive to the toxins up to 1 μM.

Article Snippet: All experimental data was analysed using QPatch Assay Software v5.0 (Biolin Scientific A/S, Ballerup, Denmark).

Techniques: Inhibition, Patch Clamp

Potency of m 3 -HwTx-IV on hNa V 1.1–1.8 stably expressed in HEK239 or CHO cells using whole-cell patch-clamp electrophysiology in QPatch and heterologously expressed in HEK293 cells assessed using FLIPR membrane potential assay. Data are presented as IC 50 mean ± SD.

Journal: PLoS ONE

Article Title: The structure, dynamics and selectivity profile of a Na V 1.7 potency-optimised huwentoxin-IV variant

doi: 10.1371/journal.pone.0173551

Figure Lengend Snippet: Potency of m 3 -HwTx-IV on hNa V 1.1–1.8 stably expressed in HEK239 or CHO cells using whole-cell patch-clamp electrophysiology in QPatch and heterologously expressed in HEK293 cells assessed using FLIPR membrane potential assay. Data are presented as IC 50 mean ± SD.

Article Snippet: All experimental data was analysed using QPatch Assay Software v5.0 (Biolin Scientific A/S, Ballerup, Denmark).

Techniques: Stable Transfection, Patch Clamp, Membrane